Systems Summit on Healthcare Transformation
Date & Time
Nov 06 -
07 2025
1:00 PM - 9:00 PM
Speaker(s)
Experts from both medicine and policy spheres
Audience
By Invitation Only
The 2025 Systems Summit on Healthcare Transformation is sponsored by the American Medical Association and will take place November 6-7 at Princeton University. The Systems Summit, last held in 2023, is a special event that brings together preeminent national thought leaders for an unparalleled, systems-level exploration of pressing topics in healthcare.
The 2025 Systems Summit will explore the future of healthcare A.I., clinical innovation, and the rapidly shifting landscape in health policy and economics. Specifically, the summit will examine the often-overlooked systems issues that must be addressed to optimize integration of A.I. in healthcare, including incentive and reimbursement structures, clinical workflows, infrastructure demands, accountability and regulatory concerns, and workforce upskilling / deskilling and scope of practice issues. The event will also highlight opportunities for healthcare transformation through novel approaches to population health, clinical entrepreneurship, alternative payment and care delivery models, and transformative public policy.
The goal of the event is to shape national discourse, public policy, and healthcare institutional strategy to create a more effective overall health system for the nation. This one-of-a-kind event is limited to fewer than 100 distinguished guests and is by invitation only.
Please direct all questions to conference organizers at systemssummit@princeton.edu.
This event is not open to the public.
Sponsorship of an event does not constitute institutional endorsement of external speakers or views presented.
Agenda
Thursday, November 6, 2025
12:00 PM – Registration Opens
1:00 PM – Systems Summit Begins
- Opening Remarks: Kim Lomis, MD, Vice President, Medical Education Innovations, American Medical Association
- A.I. Snake Oil: What Artificial Intelligence Can Do, What it Can’t, and How to Tell the Difference
Arvind Narayanan, PhD, Professor of Computer Science, Director, Center for Information Technology Policy, Princeton University - A.I. in Healthcare: Are We Innovating or Just Paving Cow Paths?
Margaret Lozovatsky, MD, Vice President, Digital Health Innovations, American Medical Association
3:00 PM – Break
3:15 PM – Panel: A.I. Alone Won’t Transform Healthcare
- Moderator: Namita Seth Mohta, MD, Executive Editor, NEJM Catalyst Innovations in Care Delivery
- Brian Hasselfeld, MD, Executive Medical Director, Digital Health and Innovation, Johns Hopkins Medicine
- Chethan Sarabu, MD, Director of Clinical Innovation, Cornell Tech
- Kathleen Lee, MD, Associate Vice President, Associate Chief Transformation Officer, Penn Medicine
4:10 PM – Closing Reflection: Sanjay Desai, MD, Senior Vice President, Chief Academic Officer, American Medical Association
6:00 PM – Summit Evening Reception
7:00 PM – Summit Dinner and Fireside Chat
- Welcome: Paul Lipton, PhD, Senior Associate Dean, School of Public and International Affairs, Princeton University
- Opening Remarks: Bryant Adibe, MD, MS, Practitioner in Residence, Faculty Chair, Systems Summit Planning Committee, School of Public and International Affairs, Princeton University
- Featured Fireside Chat: Reflections on the State of American Healthcare
- Monica Bertagnolli, MD, President-Elect, National Academy of Medicine; Fmr. Director, National Institutes of Health (NIH)
- Chiquita Brooks-LaSure, MPP, Sr. Fellow, The Century Foundation; Fmr. Administrator, Centers for Medicare and Medicaid Services (CMS)
Acknowledgement: Jesse Ehrenfeld, MD, MPH, Senior Associate Dean, Medical College of Wisconsin; Fmr. President, American Medical Association (*not in attendance)
Friday, November 7, 2025
7:15 AM – Breakfast & Registration
8:15 AM – Opening Remarks: Wayne Jonas, MD, President, Healing Works Foundation
Opening Keynote: Mitch Katz, MD, President & CEO, NYC Health + Hospitals
9:00 AM – Panel: Fostering Innovation and Agility in a Dynamic Policy Environment
- Moderator: Sarah Meier, PhD, M.Sc., Director, Payment and Care Delivery Policy, Mayo Clinic
- John Ayanian, MD, MPP, Director, Institute for Healthcare Policy and Innovation; Alice Hamilton Distinguished University Professor of Medicine and Healthcare Policy, University of Michigan
- Chris DeRienzo, MD, MPP, Senior Vice President, Chief Physician Executive, American Hospital Association
- Larry Levitt, MPP, Executive Vice President for Health Policy, KFF
10:00 AM – Blitz Talks: Transforming Primary Care in Under-Resourced Environments
- Blitz #1: Alan Roth, DO, Chair, Department of Family Medicine and Ambulatory Care; Chief, Division of Integrative Pain and Palliative Care, Medisys, Jamaica Hospital Medical Center
- Blitz #2: Jeff Brenner, MD, CEO, The Jewish Board, Fmr. CEO, Camden Coalition
10:45 AM – Break
11:00 AM – Panel: Healthcare’s Social Transformation: Regaining Trust in the Age of A.I.
- Moderator: Heather Howard, JD, Professor of the Practice and Director, State Health and Value Strategies; Co-Director, Global Health Program, Center for Health and Wellbeing, Princeton University
- Paul Starr, PhD, Stuart Professor of Communications and Public Affairs; Professor of Sociology and Public Affairs; Pulitzer-Prize winning author, The Social Transformation of American Medicine
- Reed Tuckson, MD, Co-Founder / Board Chair, The Coalition for Trust in Health & Science, Fmr. Executive Vice President and Chief of Medical Affairs, UnitedHealth Group
12:00 PM – Lunch
Lunchtime Featured Talks: Innovations for the Healthcare Workforce
- Blitz Talk #1: Alidad Ghiassi, MD, Chief Medical Officer and Co-Founder, HIA Technologies; Fmr. Clinical Assistant Professor of Orthopedic Surgery, Keck School of Medicine of USC
- Blitz Talk #2: Sunita Mutha, MD, Director, Healthforce Center at UCSF, Professor of Medicine, UCSF School of Medicine
1:00 PM – Thematic Breakout Groups: Policy, Economics, Technology
1:45 PM – Open Discussion: Takeaways from Breakout Groups
2:15 PM – Closing Reflections
2:30 PM – Systems Summit Adjourns
LOGISTICS
Princeton University provides a wide range of planning suggestions on its website. We have highlighted the most useful information here.
Transportation to Princeton University
Princeton is accessible by four international airports; Newark and Philadelphia are the nearest. Please note that Princeton University is located approximately 1-hour away from Newark or Philadelphia by car, contingent on traffic.
New Jersey Transit operates local train routes in the area.
Princeton University is easily accessible from the New York metropolitan area via NJ TRANSIT's Northeast Corridor line. NJ TRANSIT trains passing through Princeton Junction provide direct service to New York City and Newark Liberty International Airport.
Amtrak trains connect Princeton Junction to NYC, Philadelphia, Washington, D.C., Boston and the broader region. Amtrak also has frequent service to Trenton (Trenton Transit Center) located 10 miles from campus, where you can get a taxi to campus.
A train known locally as “The Dinky” connects campus (Princeton Station at Alexander Street) to the Princeton Junction station. A southbound transfer to the SEPTA regional rail Trenton Line train at Trenton provides service to Philadelphia.
After taking the train to the Princeton Junction stop, take the Princeton Shuttle (the "Dinky") train for a five-minute ride to Princeton Station, located on the university campus.
Campus is located in Princeton, N.J., approximately one mile west of U.S. Route 1.
In addition to Uber/Lyft, traditional car service is available in the area through A-1 Limousine or Gem Ground Transportation.
A visitor parking permit is available for free for use in the Stadium Drive Garage. Follow the link, select the first date you will be on campus and enter your email address and the details of your vehicle and license plate. Two shuttle routes serve the Stadium Drive Garage during the day.
Time table for garage to McCosh/Robertson: Route #1 and Route #4
Time table for McCosh/Robertson to garage: Route #1 and Route #4
Between 7pm and midnight, you should board the Route #5 - Evening circulator and ask the driver to stop at the Stadium Drive garage.
For more information, including a full shuttle map and schedule, please see the Princeton University Transportation & Parking website.
Accommodations
In addition to the Nassau Inn, Peacock Inn, and the Graduate Hotel in the heart of downtown Princeton, we suggest attendees book their accommodations at the Hyatt Regency Princeton, a short complimentary shuttle away from the System Summit events.